Jing Wang-Hughes is a board-certified endocrinologist and physician-scientist. My lab at Washington University studies pancreatic islet function in diabetes. Our work is anchored in fundamental questions of how primary cilia sense nutrients and mediate islet cell crosstalk. We use quantitative microscopy as well as standard molecular biology, biochemistry, genetic, and in vivo approaches to study islet cilia signaling and motility, and we frequently collaborate with colleagues in the islet and cilia fields with complementary interests and techniques. Current efforts in my lab are focused on defining cilia localization and distribution in human pancreatic islets, focusing on T1D and T2D-related changes that correlate with human disease.