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    Pfizer Reports Second-Quarter 2010 Results

    -- Second-Quarter 2010 Revenues of $17.3 Billion -- Second-Quarter 2010 Reported Diluted EPS(1) of $0.31, Adjusted Diluted EPS(2) of $0.62 -- Reaffirms 2010 Financial Guidance and 2012 Financial Targets -- Strong Quarterly Performance Reflects More Balanced Business Mix and Product Portfolio

    (BUSINESS WIRE)--

     

    ($ in millions, except per share amounts)                
      Second-Quarter   Year-to-Date
        2010   2009   Change   2010   2009   Change
    Reported Revenues $ 17,327   $ 10,984   58 %   $ 34,077   $ 21,851   56 %

    Reported Net Income(1)

      2,475   2,261   9 %   4,501   4,990   (10 %)

    Reported Diluted EPS(1)

      0.31   0.34   (9 %)   0.56   0.74   (24 %)

    Adjusted Income(2)

      4,959   3,249   53 %   9,841   6,916   42 %

    Adjusted Diluted EPS(2)

      0.62   0.48   29 %   1.22   1.03   18 %
                           
     
    See end of text prior to tables for notes.

    Pfizer Inc. (NYSE: PFE) today reported financial results for second-quarter 2010. Since the acquisition of Wyeth was completed on October 15, 2009, legacy Wyeth products and operations are reflected in the first two quarters of 2010, but not reflected in the first two quarters of 2009. Second-quarter 2010 revenues were $17.3 billion, an increase of 58% compared with $11.0 billion in the year-ago quarter. Revenues for second-quarter 2010 compared with the year-ago quarter were favorably impacted by $5.4 billion, or 50%, due to the addition of the legacy Wyeth products, by $315 million, or 3%, due to legacy Pfizer products, and by $584 million, or 5%, due to foreign exchange. For second-quarter 2010, U.S. revenues were $7.4 billion, an increase of 63% compared with the year-ago quarter. International revenues were $9.9 billion, an increase of 54% compared with the prior-year quarter, which reflected 45% operational growth and a 9% favorable impact of foreign exchange. U.S. revenues represented 43% of total revenues in second-quarter 2010 compared with 41% in the year-ago quarter, while international revenues represented 57% of total revenues in second-quarter 2010 compared with 59% in the year-ago quarter.

    For first-half 2010, revenues were $34.1 billion, an increase of 56% compared with $21.9 billion in the same period in 2009. Revenues for first-half 2010 compared with the year-ago period were favorably impacted by $10.7 billion, or 49%, due to the addition of the legacy Wyeth products, by $173 million, or 1%, due to legacy Pfizer products, and by $1.3 billion, or 6%, due to foreign exchange. U.S. revenues were $14.7 billion, an increase of 55% compared with first-half 2009. International revenues were $19.4 billion, an increase of 57% compared with the same period last year, which reflected 46% operational growth and an 11% favorable impact of foreign exchange. U.S. revenues represented 43% and international revenues represented 57% of the total in first-half 2010, both comparable with first-half 2009.

    Business Revenues

    Pfizer operates two distinct commercial organizations: Biopharmaceutical and Diversified. Biopharmaceutical includes the Primary Care, Specialty Care, Established Products, Emerging Markets and Oncology customer-focused units, while Diversified includes Animal Health, Consumer Healthcare, Nutrition and Capsugel.

     
     
     

    Second-Quarter(13)

                        Operational
    ($ in millions)   2010    

    2009(13)

      Change     Foreign
    Exchange
      Total   Legacy Pfizer
                             

    Primary Care(3)

    $ 5,923   $ 5,160     15 %     3 %   12 %   5 %

    Specialty Care(4)

      3,769     1,423     165 %     5 %   160 %   8 %

    Established Products(5)

      2,730     1,670     63 %     5 %   58 %   (10 %)

    Emerging Markets(6)

      2,250     1,455     55 %     11 %   44 %   11 %

    Oncology(7)

      349     355     (2 %)     2 %   (4 %)   (14 %)
                             
    Biopharmaceutical   15,021     10,063     49 %     5 %   44 %   3 %
                             

    Animal Health(8)

      893     648     38 %     7 %   31 %   2 %

    Consumer Healthcare(9)

      678     --     N/A       N/A     N/A     N/A  

    Nutrition(10)

      476     --     N/A       N/A     N/A     N/A  

    Capsugel(11)

      195     185     5 %     1 %   4 %   4 %
                             
    Diversified   2,242     833     169 %     12 %   157 %   3 %
                             

    Other(12)

      64     88     (27 %)     (3 %)   (24 %)   (24 %)
                             
    Total $ 17,327   $ 10,984     58 %     5 %   53 %   3 %
                             
    See end of text prior to tables for notes.
     
    N/A – Not applicable

    For second-quarter 2010, revenues from Biopharmaceutical were $15.0 billion, an increase of 49% compared with $10.1 billion in the year-ago quarter. Operationally, revenues increased $4.5 billion, or 44%, which included $4.2 billion, or 41%, attributable to legacy Wyeth products, primarily Premarin in the Primary Care unit, Enbrel and the Prevnar/Prevenar franchise in the Specialty Care unit, Effexor in the Established Products unit as well as Enbrel and Prevenar in the Emerging Markets unit, and $313 million, or 3%, due to legacy Pfizer products. In addition, foreign exchange favorably impacted Biopharmaceutical revenues by 5% or $485 million.

    Within the Biopharmaceutical units, legacy Pfizer operational performance was impacted in second-quarter 2010 compared with the year-ago quarter by the loss of exclusivity of certain products and by the resulting reclassification of Camptosar revenues among the units. Legacy Pfizer Oncology unit revenues no longer include Camptosar's European revenues due to its loss of exclusivity in July 2009. Camptosar's European revenues are included in the Established Products unit beginning in first-quarter 2010. This reclassification of revenues negatively impacted the Oncology unit's performance by 20% in second-quarter 2010 compared with the prior-year quarter. Further, legacy Pfizer Established Products unit revenues in second-quarter 2010 were adversely impacted by 5% due to the loss of exclusivity for Norvasc in Canada in July 2009, partially offset by the favorable impact of 1% due to the addition of Camptosar's European revenues.

    For second-quarter 2010, revenues from Diversified were $2.2 billion, an increase of 169% compared with $833 million in the year-ago quarter. Operationally, revenues increased $1.3 billion, or 157%, which was primarily attributable to legacy Wyeth products, principally Centrum, Advil and Caltrate in Consumer Healthcare and infant and toddler Nutrition products. Additionally, foreign exchange favorably impacted Diversified revenues by 12% or $102 million.

    Reported Net Income(1) and Reported Diluted EPS(1)

    For second-quarter 2010, Pfizer posted reported net income(1) of $2.5 billion, an increase of 9% compared with $2.3 billion in the prior-year quarter, and reported diluted EPS(1) of $0.31, a decrease of 9% compared with $0.34 in the prior-year quarter. For first-half 2010, Pfizer posted reported net income(1) of $4.5 billion, a decrease of 10% compared with $5.0 billion in first-half 2009, and reported diluted EPS(1) of $0.56, a decline of 24% compared with $0.74 in the prior-year period. Results were favorably impacted by revenues from legacy Wyeth products and foreign exchange, and negatively impacted by the expenses associated with the legacy Wyeth operations as well as purchase accounting adjustments, integration charges and restructuring charges associated with the Wyeth acquisition, higher net interest expense primarily due to the borrowings used to partially fund the Wyeth acquisition and an increase in the effective tax rate.

    The effective tax rate on reported results increased to approximately 37% in second-quarter 2010 from approximately 26% in second-quarter 2009, and approximately 37% in first-half 2010 compared with approximately 27% in first-half 2009. These increases were primarily the result of higher charges incurred as a result of the acquisition of Wyeth and the mix of jurisdictions in which those charges were incurred.

    Additionally, reported diluted EPS(1) in second-quarter 2010 and first-half 2010 was impacted by the increased number of shares outstanding in comparison with the corresponding periods in 2009 resulting from shares issued to partially fund the Wyeth acquisition.

    Adjusted Income(2) and Adjusted Diluted EPS(2)

    Second-quarter 2010 adjusted income(2) was $5.0 billion, an increase of 53% compared with $3.2 billion in the year-ago quarter, and adjusted diluted EPS(2) was $0.62, an increase of 29% compared with $0.48 in the year-ago quarter. For first-half 2010, Pfizer posted adjusted income(2) of $9.8 billion, an increase of 42% compared with $6.9 billion in first-half 2009, and adjusted diluted EPS(2) of $1.22, an increase of 18% compared with $1.03 in the prior-year period. Results were favorably impacted by revenues from legacy Wyeth products and foreign exchange, which were partially offset by the expenses associated with the legacy Wyeth operations as well as higher net interest expense primarily due to the borrowings used to partially fund the acquisition of Wyeth and an increase in the effective tax rate.

    The effective tax rate on adjusted income(2) increased to approximately 32% in second-quarter 2010 compared with approximately 28% in second-quarter 2009, and approximately 31% in first-half 2010 compared with approximately 29% in first-half 2009. These increases were primarily the result of certain business decisions made in connection with the acquisition of Wyeth and the change in the jurisdictional mix of earnings.

    Additionally, adjusted diluted EPS(2) in second-quarter 2010 and first-half 2010 was impacted by the increased number of shares outstanding in comparison with the corresponding periods in 2009 resulting from shares issued to partially fund the Wyeth acquisition.

    In second-quarter 2010, adjusted cost of sales(2) as a percentage of revenues was 17.0% compared with 15.4% in second-quarter 2009. This increase primarily reflects the change in the mix of products and businesses as a result of the Wyeth acquisition. Excluding the impact of foreign exchange, adjusted cost of sales(2) as a percentage of revenues was 18.2% in second-quarter 2010.

    Adjusted SI&A expenses(2) were $4.7 billion in second-quarter 2010, an increase of 45% compared with $3.3 billion in the prior-year quarter. This increase was attributable primarily to the addition of the legacy Wyeth operations. Foreign exchange increased second-quarter 2010 adjusted SI&A expenses(2) by $126 million compared with the year-ago quarter.

    Adjusted R&D expenses(2) were $2.2 billion in second-quarter 2010, an increase of 32% compared with $1.7 billion in the prior-year period. This increase was attributable primarily to the addition of the legacy Wyeth operations and continued investment in the late-stage development portfolio. Foreign exchange increased second-quarter 2010 adjusted R&D expenses(2) by $21 million compared with the year-ago quarter.

    Overall, foreign exchange increased adjusted total costs(14) by $48 million, or 1%, in second-quarter 2010 compared with the prior-year period.

    Executive Commentary

    Jeff Kindler, Chairman and Chief Executive Officer, stated, "During the quarter, Pfizer's more balanced global portfolio, which includes small molecules, biologics and vaccines as well as off-patent pharmaceuticals and diversified products generated strong performance in a period of notable worldwide economic uncertainty. Within our Biopharmaceutical businesses, our recently launched vaccine for the prevention of pneumococcal disease in children, Prevnar/Prevenar 13, was a strong contributor, while many key products in our Primary Care, Specialty Care and Oncology units also performed well on a global basis. The Emerging Markets unit continued to benefit from our on-going investment, with year-over-year operational growth on a legacy Pfizer basis of 11%(13). Within that unit, revenues in our six key markets, led by China, increased a combined 19% on a legacy Pfizer operational basis to approximately $800 million."

    "We continue to make solid progress on the Wyeth integration while we remain focused on delivering strong business performance. We expect to receive phase three clinical data for tasocitinib in rheumatoid arthritis, Sutent in lung cancer, Prevnar 13 for the prevention of pneumococcal disease in adults, axitinib in renal cell carcinoma and bosutinib in chronic myelogenous leukemia during the balance of this year. Within the Established Products unit, we anticipate continued new product launches, and within the Emerging Markets unit, we plan to continue our expansion in China and other key markets. Within our Diversified businesses, we plan to continue launching new innovations in markets around the world to grow and strengthen our product offerings, such as in our vitamin and infant formula product lines. We believe that these actions, in addition to a modest level of business development, will continue to support consistent, solid financial results," continued Mr. Kindler.

    Frank D'Amelio, Chief Financial Officer, stated, "Based on our year-to-date performance, continued confidence in the business, progress on both our cost-reduction initiatives and the Wyeth integration as well as our future outlook, we are reaffirming our 2010 financial guidance and our 2012 financial targets. At this point, we anticipate that 2010 adjusted diluted EPS(2) will be at the upper-end of our guidance range, with expenses at the lower-end of our ranges. Given the continued strength of our balance sheet and significant operating cash flow, we remain confident that we have the financial wherewithal to successfully execute our strategies and continue to meet our financial objectives. Additionally, during the second quarter, we repurchased approximately $500 million, or 31 million shares, of our common stock."

    2010 Financial Guidance(16)

    For full-year 2010, Pfizer's financial guidance, at current exchange rates(15), is summarized below.

       
    Reported Revenues $67.0 to $69.0 billion  

    Adjusted Cost of Sales(2) as a Percentage of Revenues

    19.0% to 20.0%  

    Adjusted SI&A Expenses(2)

    $19.0 to $20.0 billion  

    Adjusted R&D Expenses(2)

    $9.1 to $9.6 billion  

    Adjusted Other (Income)/Deductions(2)

    $1.2 to $1.4 billion  

    Effective Tax Rate on Adjusted Income(2)

    Approximately 30%  

    Reported Diluted EPS(1)

    $0.95 to $1.10  

    Adjusted Diluted EPS(2)

    $2.10 to $2.20  

    2012 Financial Targets

    The Company is reaffirming all elements of its 2012 financial targets. As previously stated, given the longer-term nature of these targets, they are subject to greater variability and less certainty as a result of potential material impacts related to foreign exchange fluctuations, macroeconomic activity including inflation, and industry-specific challenges including changes to government healthcare policy, among others.

    For 2012, at current exchange rates(15), Pfizer is targeting reported revenues between $65.2 and $67.7 billion, reported diluted EPS(1) between $1.58 and $1.73, adjusted diluted EPS(2) between $2.25 and $2.35, adjusted R&D expenses(2) between $8.0 and $8.5 billion, adjusted operating margin(2) in a range of the high 30%s to low 40%s and adjusted other (income)/deductions(2) between $1.0 and $1.2 billion in deductions. The effective tax rate on adjusted income(2) is targeted at approximately 30%, while operating cash flow is expected to be at least $19.0 billion.

    Additionally, the Company remains on-track to achieve the cost-reduction target of approximately $4 to $5 billion, by the end of 2012, at 2008 average foreign exchange rates, in comparison with the 2008 pro-forma adjusted total costs(14) of Pfizer and the legacy Wyeth operations.

    For additional details, please see the attached financial schedules, product revenue tables, supplemental information and disclosure notice.

    1. "Reported Net Income" is defined as net income attributable to Pfizer Inc. in accordance with U.S. generally accepted accounting principles. "Reported Diluted EPS" is defined as reported diluted EPS attributable to Pfizer Inc. common shareholders in accordance with U.S. generally accepted accounting principles.
    2. "Adjusted Income" and its components and "Adjusted Diluted Earnings Per Share (EPS)" are defined as reported net income(1) and its components and reported diluted EPS(1) excluding purchase accounting adjustments, acquisition-related costs, discontinued operations and certain significant items. Adjusted Cost of Sales, Adjusted SI&A expenses, Adjusted R&D expenses and Adjusted Other (Income)/Deductions are income statement line items prepared on the same basis, and therefore, components of the overall adjusted income measure. As described under AdjustedIncome in the Management's Discussion and Analysis of Financial Condition and Results of Operations section of Pfizer's Form 10-Q for the fiscal quarter ended April 4, 2010, management uses adjusted income, among other factors, to set performance goals and to measure the performance of the overall company. We believe that investors' understanding of our performance is enhanced by disclosing this measure. Reconciliations of second-quarter 2010 and 2009 and first-half 2010 and 2009 adjusted income and its components and adjusted diluted EPS to reported net income(1) and its components and reported diluted EPS(1), as well as reconciliations of full-year 2010 guidance and 2012 targets for adjusted income and adjusted diluted EPS to full-year 2010 guidance and 2012 targets for reported net income(1) and reported diluted EPS(1), are provided in the materials accompanying this report. The adjusted income and its components and adjusted diluted EPS measures are not, and should not be viewed as, substitutes for U.S. GAAP net income and its components and diluted EPS.
    3. The Primary Care unit includes revenues from human pharmaceutical products primarily prescribed by primary-care physicians, and may include, but are not limited to, products in the following therapeutic and disease areas: Alzheimer's disease, anxiety, cardiovascular (excluding pulmonary arterial hypertension), diabetes, pain, genitourinary, obesity, osteoporosis and respiratory. Examples of products in this unit include, but are not limited to, Celebrex, Lipitor, Lyrica, Premarin, Pristiq and Viagra. All revenues for such products are allocated to the Primary Care unit, except those generated in emerging markets(6) and those that are managed by the Established Products(5) unit.
    4. The Specialty Care unit includes revenues from human pharmaceutical products primarily prescribed by physicians who are specialists, and may include, but are not limited to, products in the following therapeutic and disease areas: antibacterials, antifungals, antivirals, bone, inflammation, gastrointestinal, growth hormones, multiple sclerosis, ophthalmology, pulmonary arterial hypertension and psychosis. Examples of products in this unit include, but are not limited to, Enbrel, Genotropin, Geodon, the Prevnar/Prevenar franchise, Xalatan and Zyvox. All revenues for such products are allocated to the Specialty Care unit, except those generated in emerging markets(6) and those that are managed by the Established Products(5) unit.
    5. The Established Products unit generally includes revenues from human prescription pharmaceutical products that have lost patent protection or marketing exclusivity in certain countries and/or regions. In certain situations, products may be transferred to this unit before losing patent protection or marketing exclusivity in order to maximize their value. This unit also excludes revenues generated in emerging markets(6). Examples of products in this unit include, but are not limited to, Arthrotec, Effexor, Medrol, Norvasc and Relpax.
    6. The Emerging Markets unit includes revenues from all human prescription pharmaceutical products sold in emerging markets, including, but not limited to, Asia (excluding Japan and South Korea), Latin America, Middle East, Africa, Central and Eastern Europe, Russia and Turkey.
    7. The Oncology unit includes revenues from human oncology and oncology-related products. Examples of products in this unit include, but are not limited to, Aromasin, Sutent and Torisel. All revenues for such products are allocated to the Oncology unit, except those generated in emerging markets(6) and those that are managed by the Established Products(5) unit.
    8. Animal Health includes worldwide revenues from products to prevent and treat disease in livestock and companion animals, including vaccines, paraciticides and anti-infectives.
    9. Consumer Healthcare generally includes worldwide revenues from non-prescription medicines and vitamins and may include, but are not limited to, products in the following therapeutic categories: pain management, nutritionals, respiratory and GI-topicals. Examples of products in Consumer Healthcare include, but are not limited to, Advil, Centrum, Caltrate, ChapStick and Robitussin.
    10. Nutrition generally includes revenues from a full line of infant and toddler nutritional products sold outside of North America. Examples of products in Nutrition include, but are not limited to, the S-26 and SMA product lines as well as formula for infants with special nutritional needs.
    11. Capsugel generally includes worldwide revenues from capsule products and services for the pharmaceutical and associated healthcare industries.
    12. Includes revenues generated primarily from Pfizer Centersource.
    13. In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.
    14. Represents the total of Adjusted Cost of Sales(2), Adjusted SI&A expenses(2) and Adjusted R&D expenses(2).
    15. The current exchange rates assumed in connection with the 2010 financial guidance are a blend of the average of the actual exchange rates in effect during first-half 2010 and the mid-July 2010 exchange rates for the remainder of the year. The current exchanges rates assumed in connection with the 2012 financial targets are the mid-July 2010 exchange rates.
    16. This guidance does not assume the completion of any business-development transactions not completed as of July 4, 2010. This guidance also excludes the potential effects of the resolution of litigation-related matters not substantially resolved as of July 4, 2010.

    PFIZER INC. AND SUBSIDIARY COMPANIES
    CONSOLIDATED STATEMENTS OF INCOME
    (UNAUDITED)
    (millions, except per common share data)

     
          Second Quarter   % Incr. /   Six Months   % Incr. /
          2010     2009   (Decr.)   2010   2009   (Decr.)
      Revenues $ 17,327     $ 10,984   58     $ 34,077   $ 21,851   56  
      Costs and expenses:                              
       

    Cost of sales (a)

      3,795       1,756   116       8,101     3,164   156  
       

    Selling, informational and administrative expenses (a)

      4,807       3,350   43       9,243     6,226   48  
       

    Research and development expenses (a)

      2,187       1,695   29       4,413     3,400   30  
        Amortization of intangible assets   1,407       583   141       2,816     1,161   143  
        Acquisition-related in-process research and development charges   -       20   *     74     20   270  
        Restructuring charges and certain acquisition-related costs   886       459   93       1,592     1,013   57  
        Other (income)/deductions--net   271       72   276       685     15   *
      Income from continuing operations before provision                              
        for taxes on income   3,974       3,049   30       7,153     6,852   4  
      Provision for taxes on income   1,488       786   89       2,634     1,860   42  
      Income from continuing operations   2,486       2,263   10       4,519     4,992   (9 )
      Discontinued operations--net of tax   (1 )     3   (133 )     1     4   (75 )
      Net income before allocation to noncontrolling interests   2,485       2,266   10       4,520     4,996   (10 )
      Less: Net income attributable to noncontrolling interests   10       5   100       19     6   217  
      Net income attributable to Pfizer Inc. $ 2,475     $ 2,261   9     $ 4,501   $ 4,990   (10 )
      Earnings per share - basic:                              
        Income from continuing operations attributable to Pfizer Inc. common shareholders $ 0.31     $ 0.34   (9 )   $ 0.56   $ 0.74   (24 )
        Discontinued operations--net of tax   -       -   --       -     -   --  
        Net income attributable to Pfizer Inc. common shareholders $ 0.31     $ 0.34   (9 )   $ 0.56   $ 0.74   (24 )
      Earnings per share - diluted:                              
        Income from continuing operations attributable to Pfizer Inc. common shareholders $ 0.31     $ 0.34   (9 )   $ 0.56   $ 0.74   (24 )
        Discontinued operations--net of tax   -       -   --       -     -   --  
        Net income attributable to Pfizer Inc. common shareholders $ 0.31     $ 0.34   (9 )   $ 0.56   $ 0.74   (24 )
      Weighted-average shares used to calculate earnings per common share:                              
        Basic   8,046       6,728         8,053     6,726    
        Diluted   8,072       6,752         8,085     6,752    
                                       
                                       
    (a) Exclusive of amortization of intangible assets, except as discussed in footnote 5 below.
      * Calculation not meaningful.
      Certain amounts and percentages may reflect rounding adjustments.
       
    1. The above financial statements present the three-month and six-month periods ended July 4, 2010 and June 28, 2009. Subsidiaries
      operating outside the United States are included for the three-month and six-month periods ended May 31, 2010 and May 24, 2009.
      Wyeth's results are included in our consolidated financial statements commencing from the acquisition date of October 15, 2009,
      in accordance with Pfizer's domestic and international year-ends. Therefore, our results of operations for the three-month and six-
      month periods ended June 28, 2009 do not include Wyeth's results of operations. Cost of sales for 2010 includes the significant impacts
      of purchase accounting adjustments associated with inventory acquired from Wyeth that was sold in 2010. Amortization of intangible assets
      for 2010 includes the amortization of intangible assets acquired from Wyeth.
    2. The financial results for the three-month and six-month periods ended July 4, 2010, are not necessarily indicative of the results which
      could ultimately be achieved for the current year.
    3. Included in Restructuring charges and certain acquisition-related costs for the three-month and six-month periods ended June 28, 2009 are $184 million
      and $553 million, respectively, of transaction costs, such as banking, legal, accounting and other similar costs, directly related to our acquisition of Wyeth.
    4. In the first six months of 2010, we recorded $74 million of Acquisition-related in-process research and development charges (IPR&D) due to the
      resolution of contingencies associated with our 2008 acquisition of CovX. In the second quarter of 2009, we recorded $20 million of
      IPR&D due to the resolution of contingencies associated with our 2008 acquisition of CovX.
    5. Amortization expense related to acquired intangible assets that contribute to our ability to sell, manufacture, research, market and
      distribute our products is included in Amortization of intangible assets as these intangible assets benefit multiple business functions.
      Amortization expense related to acquired intangible assets that are associated with a single function is included in Cost of sales,
     

    Selling, informational and administrative expenses or Research and development expenses, as appropriate.

    PFIZER INC. AND SUBSIDIARY COMPANIES
    RECONCILIATION OF REPORTED NET INCOME ATTRIBUTABLE TO PFIZER INC. AND ITS COMPONENTS
    AND REPORTED DILUTED EPS ATTRIBUTABLE TO PFIZER INC. COMMON SHAREHOLDERS

    TO ADJUSTED INCOME AND ITS COMPONENTS AND ADJUSTED DILUTED EPS (a)

    (UNAUDITED)
    (millions of dollars, except per common share data)
       
          Quarter Ended July 4, 2010
              Purchase   Acquisition-       Certain    
              Accounting   Related   Discontinued   Significant    
          Reported

     

    Adjustments

      Costs(2)   Operations   Items(3)   Adjusted
    Revenues $ 17,327 $ - $ - $ - $ (6) $ 17,321
    Costs and expenses:                        
      Cost of sales (b)   3,795   (727)   (113)   -   (4)   2,951
      Selling, informational and administrative expenses (b)   4,807   10   (102)   -   12   4,727
      Research and development expenses (b)   2,187   (5)   -   -   -   2,182
      Amortization of intangible assets   1,407   (1,373)   -   -   -   34
      Acquisition-related in-process research and development charges   -   -   -   -   -   -
      Restructuring charges and certain acquisition-related costs   886   -   (886)   -   -   -
      Other (income)/deductions--net   271   (3)   -   -   (111)   157
    Income from continuing operations before provision                        
      for taxes on income   3,974   2,098   1,101   -   97   7,270
    Provision for taxes on income   1,488   540   237   -   36   2,301
    Income from continuing operations   2,486   1,558   864   -   61   4,969
    Discontinued operations--net of tax   (1)   -   -   1   -   -
    Net income before allocation to noncontrolling interests   2,485   1,558   864   1   61   4,969
    Less: Net income attributable to noncontrolling interests   10   -   -   -   -   10
    Net income attributable to Pfizer Inc. $ 2,475 $ 1,558 $ 864 $ 1 $ 61 $ 4,959
    Earnings per common share - diluted:                        
      Income from continuing operations attributable to Pfizer Inc.                        
      common shareholders $ 0.31 $ 0.19 $ 0.11 $ - $ 0.01 $ 0.62
      Discontinued operations--net of tax   -   -   -   -   -   -
      Net income attributable to Pfizer Inc. common shareholders $ 0.31 $ 0.19 $ 0.11 $ - $ 0.01 $ 0.62
          Six Months Ended July 4, 2010
              Purchase   Acquisition-       Certain    
              Accounting   Related   Discontinued   Significant    
          Reported

     

    Adjustments

      Costs(2)   Operations   Items(3)   Adjusted
    Revenues $ 34,077 $ -   $ -   $ -   $ (13 ) $ 34,064
    Costs and expenses:                        
      Cost of sales (b)   8,101   (2,077 )   (126 )   -     (12 )   5,886
      Selling, informational and administrative expenses (b)   9,243   9     (162 )   -     12     9,102
      Research and development expenses (b)   4,413   (15 )   (20 )   -     -     4,378
      Amortization of intangible assets   2,816   (2,756 )   -     -     -     60
      Acquisition-related in-process research and development charges   74   (74 )   -     -     -     -
      Restructuring charges and certain acquisition-related costs   1,592   -     (1,592 )   -     -     -
      Other (income)/deductions--net   685   (26 )   -     -     (292 )   367
    Income from continuing operations before provision                        
      for taxes on income   7,153   4,939     1,900     -     279     14,271
    Provision for taxes on income   2,634   1,252     463     -     62     4,411
    Income from continuing operations   4,519   3,687     1,437     -     217     9,860
    Discontinued operations--net of tax   1   -     -     (1 )   -     -
    Net income before allocation to noncontrolling interests   4,520   3,687     1,437     (1 )   217     9,860
    Less: Net income attributable to noncontrolling interests   19   -     -     -     -     19
    Net income attributable to Pfizer Inc. $ 4,501 $ 3,687   $ 1,437   $ (1 ) $ 217   $ 9,841
    Earnings per common share - diluted:                        
      Income from continuing operations attributable to Pfizer Inc.                        
      common shareholders $ 0.56 $ 0.45   $ 0.18   $ -   $ 0.03   $ 1.22
      Discontinued operations--net of tax   -   -     -     -     -     -
      Net income attributable to Pfizer Inc. common shareholders $ 0.56 $ 0.45   $ 0.18   $ -   $ 0.03   $ 1.22
                               
                               
    (a) Adjusted income and its components and adjusted diluted EPS are not, and should not be viewed as, substitutes for U.S. GAAP net income and
      its components and diluted EPS.  
         
    (b) Exclusive of amortization of intangible assets, except as discussed in note 1.  
      See end of tables for notes.  
         
      Certain amounts may reflect rounding adjustments.  
    PFIZER INC. AND SUBSIDIARY COMPANIES

    RECONCILIATION OF REPORTED NET INCOME ATTRIBUTABLE TO PFIZER INC. AND ITS COMPONENTS

    AND REPORTED DILUTED EPS ATTRIBUTABLE TO PFIZER INC. COMMON SHAREHOLDERS

    TO ADJUSTED INCOME AND ITS COMPONENTS AND ADJUSTED DILUTED EPS (a)

    (UNAUDITED)
    (millions of dollars, except per common share data)
       
          Quarter Ended June 28, 2009
              Purchase   Acquisition-       Certain    
              Accounting   Related   Discontinued   Significant    
          Reported

     

    Adjustments

      Costs(2)   Operations   Items(3)   Adjusted
    Revenues $ 10,984 $ -   $ -   $ -   $ (18 ) $ 10,966  
    Costs and expenses:                        
     

    Cost of sales (b)

      1,756   -     -     -     (70 )   1,686  
     

    Selling, informational and administrative expenses (b)

      3,350   3     -     -     (89 )   3,264  
     

    Research and development expenses (b)

      1,695   (7 )   -     -     (32 )   1,656  
      Amortization of intangible assets   583   (556 )   -     -     -     27  
      Acquisition-related in-process research and development charges   20   (20 )   -     -     -     -  
      Restructuring charges and certain acquisition-related costs   459   -     (285 )   -     (174 )   -  
      Other (income)/deductions--net   72   (1 )   -     -     (263 )   (192 )
    Income from continuing operations before provision                        
      for taxes on income   3,049   581     285     -     610     4,525  
    Provision for taxes on income   786   165     100     -     220     1,271  
    Income from continuing operations   2,263   416     185     -     390     3,254  
    Discontinued operations--net of tax   3   -     -     (3 )   -     -  
    Net income before allocation to noncontrolling interests   2,266   416     185     (3 )   390     3,254  
    Less: Net income attributable to noncontrolling interests   5   -     -     -     -     5  
    Net income attributable to Pfizer Inc. $ 2,261 $ 416   $ 185   $ (3 ) $ 390   $ 3,249  
    Earnings per common share - diluted:                        
      Income from continuing operations attributable to Pfizer Inc.                        
      common shareholders $ 0.34 $ 0.06   $ 0.02   $ -   $ 0.06   $ 0.48  
      Discontinued operations--net of tax   -   -     -     -     -     -  
      Net income attributable to Pfizer Inc. common shareholders $ 0.34 $ 0.06   $ 0.02   $ -   $ 0.06   $ 0.48  
          Six Months Ended June 28, 2009
              Purchase   Acquisition-       Certain    
              Accounting   Related   Discontinued   Significant    
          Reported

     

    Adjustments

      Costs(2)   Operations   Items(3)   Adjusted
    Revenues $ 21,851 $ -   $ -   $ -   $ (40 ) $ 21,811  
    Costs and expenses:                        
     

    Cost of sales (b)

      3,164   -     -     -     (164 )   3,000  
     

    Selling, informational and administrative expenses (b)

      6,226   6     -     -     (135 )   6,097  
     

    Research and development expenses (b)

      3,400   (14 )   -     -     (65 )   3,321  
      Amortization of intangible assets   1,161   (1,096 )   -     -     -     65  
      Acquisition-related in-process research and development charges   20   (20 )   -     -     -     -  
      Restructuring charges and certain acquisition-related costs   1,013   -     (682 )   -     (331 )   -  
      Other (income)/deductions--net   15   (3 )   -     -     (428 )   (416 )
    Income from continuing operations before provision                        
      for taxes on income   6,852   1,127     682     -     1,083     9,744  
    Provision for taxes on income   1,860   357     245     -     360     2,822  
    Income from continuing operations   4,992   770     437     -     723     6,922  
    Discontinued operations--net of tax   4   -     -     (4 )   -     -  
    Net income before allocation to noncontrolling interests   4,996   770     437     (4 )   723     6,922  
    Less: Net income attributable to noncontrolling interests   6   -     -     -     -     6  
    Net income attributable to Pfizer Inc. $ 4,990 $ 770   $ 437   $ (4 ) $ 723   $ 6,916  
    Earnings per common share - diluted:                        
      Income from continuing operations attributable to Pfizer Inc.                        
      common shareholders $ 0.74 $ 0.11   $ 0.07   $ -   $ 0.11   $ 1.03  
      Discontinued operations--net of tax   -   -     -     -     -     -  
      Net income attributable to Pfizer Inc. common shareholders $ 0.74 $ 0.11   $ 0.07   $ -   $ 0.11   $ 1.03  
                               
                               
    (a) Adjusted income and its components and adjusted diluted EPS are not, and should not be viewed as, substitutes for U.S. GAAP net income and
      its components and diluted EPS.  
         
    (b) Exclusive of amortization of intangible assets, except as discussed in note 1.  
      See end of tables for notes.  
         
      Certain amounts may reflect rounding adjustments.  
    PFIZER INC. AND SUBSIDIARY COMPANIES
    RECONCILIATION OF REPORTED NET INCOME ATTRIBUTABLE TO PFIZER INC. AND ITS COMPONENTS
    AND REPORTED DILUTED EPS ATTRIBUTABLE TO PFIZER INC. COMMON SHAREHOLDERS
    TO ADJUSTED INCOME AND ITS COMPONENTS AND ADJUSTED DILUTED EPS
    (UNAUDITED)
       
                       
    1) Amortization expense related to acquired intangible assets that contribute to our ability to sell, manufacture, research, market and distribute our products is included in Amortization of intangible assets as these intangible assets benefit multiple business functions. Amortization expense related to acquired intangible assets that are associated with a single function is included in Cost of sales, Selling, informational and administrative expenses or Research and development expenses, as appropriate.
     
     
       
    2 ) Acquisition-related costs includes the following:
                       
          Second Quarter   Six Months
      (millions of dollars)   2010       2009       2010       2009  
                       
       

    Transaction costs(a)

    $ 4     $ 184     $ 13     $ 553  
       

    Integration costs(a)

      211       101       419       129  
       

    Restructuring charges(a)

      671       -       1,160       -  
       

    Additional depreciation - asset restructuring(b)

      215       -       308       -  
        Total acquisition-related costs -- pre-tax   1,101       285       1,900       682  
       

    Income taxes(c)

      (237 )     (100 )     (463 )     (245 )
        Total acquisition-related costs -- net of tax $ 864     $ 185     $ 1,437     $ 437  
                       
      (a) Transaction costs include costs directly related to our acquisition of Wyeth, such as banking, legal, accounting and other similar costs. Integration costs represent external, incremental costs directly related to integrating Wyeth and primarily include expenditures for consulting and systems integration. Restructuring charges relate to our acquisition of Wyeth and include employee termination costs, asset impairments and exit costs.
     
       
       
         
     

     

    Represents the impact of changes in the estimated useful lives of assets involved in restructuring actions related to our acquisition of Wyeth. Included in Cost of Sales ($113 million) and Selling, informational and administrative expenses ($102 million) for the three months ended July 4, 2010. Included in Cost of Sales ($126 million), Selling, informational andadministrative expenses ($162 million) and Research and development expenses ($20 million) for the six months ended July 4, 2010.
     
     

    (b)

       
       
         
      (c)

    Included in Provision for taxes on income.

    3 ) Certain significant items includes the following:
                       
          Second Quarter   Six Months
      (millions of dollars)   2010       2009       2010       2009  
                       
       

    Restructuring charges - Cost-reduction initiatives(a)

    $ -     $ 174     $ -     $ 331  
       

    Implementation costs - Cost-reduction initiatives(b)

      -       156       -       330  
       

    Certain legal matters(c)

      -       (2 )     142       130  
       

    Net interest expense(d)

      -       206       -       229  
       

    Asset impairment charges(e)

      207       66       207       66  
       

    Other(f)

      (110 )     10       (70 )     (3 )
        Total certain significant items -- pre-tax   97       610       279       1,083  
       

    Income taxes(g)

      (36 )     (220 )     (62 )     (360 )
        Total certain significant items -- net of tax $ 61     $ 390     $ 217     $ 723  
                     
      (a) Included in Restructuring charges and certain acquisition-related costs.
         
      (b) Included in Cost of sales ($45 million), Selling, informational and administrative expenses ($85 million), Research anddevelopment expenses ($32 million), and Other (income)/deductions - net ($6 million income) for the three months ended June 28, 2009. Included in Cost of sales ($121 million), Selling, informational and administrative expenses ($131 million), Research and development expenses ($73 million), and Other (income)/deductions - net ($5 million) for the six months ended June 28, 2009.
     
     
     
     
         
      (c) Included in Other (income)/deductions - net.
         
      (d) Included in Other (income)/deductions - net. Includes interest expense on the senior unsecured notes issued in connection
        with our acquisition of Wyeth less interest income earned on the proceeds of those notes.
         
      (e) Included in Other (income)/deductions - net. Primarily represents impairment charges related to in-process research and
        development (“IPR&D”) intangible assets which were acquired in connection with our acquisition of Wyeth.
         
      (f) Included in Other (income)/deductions - net. 2010 primarily represents gain on sale of certain Pfizer Animal Health
        products.
         
      (g) Included in Provision for taxes on income.
      PFIZER INC.
     

    BUSINESS REVENUES(1),(2)

      FIRST SIX MONTHS OF 2010 and 2009
      (UNAUDITED)
      (millions of dollars)
                   
       

     

         

    Operational

          2010  

    2009(2)

    Change Foreign
    Exchange
    Total Legacy
    Pfizer
      Primary Care $ 11,789 $ 10,500   12 % 4 % 8 % 2 %
      Specialty Care   7,292   2,888   152 % 7 % 145 % 3 %
      Established Products   5,514   3,329   66 % 6 % 60 % -11 %
      Emerging Markets   4,222   2,741   54 % 10 % 44 % 9 %
      Oncology   710   707   -   3 % -3 % -14 %
      Biopharmaceutical   29,527   20,165   46 % 5 % 41 % -  
                   
      Animal Health   1,739   1,185   47 % 9 % 38 % 8 %
      Consumer Healthcare   1,341   -   * * * *
      Nutrition   934   -   * * * *
      Capsugel   369   339   9 % 3 % 6 % 6 %
      Diversified   4,383   1,524   188 % 14 % 174 % 8 %
                   
      Other   167   162   3 % 1 % 2 % 2 %
                   
      TOTAL $ 34,077 $ 21,851   56 % 6 % 50 % 1 %
                   

    * -

    Calculation not meaningful

    (1)

    See notes 3-12 in the accompanying earnings release for a description of each business unit and of "Other".

    (2)

    In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.

     

     
     
     

    PFIZER INC.

    REVENUESSECOND QUARTER 2010(UNAUDITED)(millions of dollars)

     
     
     
     
     
     
     
     
       
       WORLDWIDEUNITED STATESTOTAL INTERNATIONAL(1)
                             
         2010  2009% Change    2010  2009% Change  2010  2009% Change
           TotalOper.    Total    TotalOper.
     TOTAL REVENUES$17,327$10,98458%52%$7,381$4,52463%$9,946$6,46054%45%
     TOTAL BIOPHARMACEUTICAL:$15,021$10,06349%44%$6,649$4,19059%$8,372$5,87343%34%
      Lipitor   2,813   2,685 5 % -     1,313   1,314 -     1,500   1,371 9 % 1 %
      Enbrel (Outside the U.S. and Canada)***   808   - * *   -   - *   808   - * *
      Lyrica   762   629 21 % 19 %   365   324 13 %   397   305 30 % 25 %
      Effexor***   621   - * *   492   - *   129   - * *
      Celebrex   604   548 10 % 7 %   398   390 2 %   206   158 30 % 21 %
      Viagra   491   423 16 % 12 %   234   207 13 %   257   216 19 % 11 %
      Xalatan / Xalacom   449   395 14 % 10 %   151   118 28 %   298   277 8 % 2 %
      Prevnar / Prevenar 13***   569   - * *   483   - *   86   - * *
      Prevnar / Prevenar 7***   331   - * *   33   - *   298   - * *
      Norvasc   422   518 (19 %) (23 %)   11   16 (31 %)   411   502 (18 %) (23 %)
      Zyvox   299   257 16 % 14 %   154   138 12 %   145   119 22 % 18 %
      Detrol / Detrol LA   260   273 (5 %) (7 %)   176   192 (8 %)   84   81 4 % (3 %)
      Premarin Family***   260   - * *   238   - *   22   - * *
      Sutent   255   223 14 % 11 %   62   56 11 %   193   167 16 % 11 %
      Geodon / Zeldox   247   231 7 % 6 %   205   192 7 %   42   39 8 % 2 %
      Zosyn / Tazocin***   230   - * *   150   - *   80   - * *
      Genotropin   233   207 13 % 10 %   60   50 20 %   173   157 10 % 6 %
      Vfend   207   180 15 % 12 %   63   54 17 %   144   126 14 % 10 %
      Chantix / Champix   170   192 (11 %) (16 %)   72   116 (38 %)   98   76 29 % 19 %
      Benefix***   164   - * *   77   - *   87   - * *
      Zoloft   144   125 15 % 9 %   19   22 (14 %)   125   103 21 % 14 %
      Caduet   126   128 (2 %) (6 %)   84   99 (15 %)   42   29 45 % 23 %
      Aromasin   122   114 7 % 4 %   41   39 5 %   81   75 8 % 3 %
      Revatio   122   94 30 % 27 %   75   59 27 %   47   35 34 % 26 %
      Pristiq***   113   - * *   99   - *   14   - * *
      Medrol   113   110 3 % 1 %   30   35 (14 %)   83   75 11 % 8 %
      Cardura   110   114 (4 %) (7 %)   2   2 -     108   112 (4 %) (8 %)
      Zithromax / Zmax   110   100 10 % 5 %   2   4 (50 %)   108   96 13 % 6 %
      Aricept**   103   108 (5 %) (11 %)   -   - *   103   108 (5 %) (11 %)
      Refacto / Xyntha***   98   - * *   18   - *   80   - * *
      Alliance Revenue   1,061   598 77 % 75 %   750   352 113 %   311   246 26 % 19 %
     

    (Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge)

                         
      All Other Biopharmaceutical   2,604   1,811 44 % 38 %   792   411 93 %   1,812   1,400 29 % 22 %
      All Other Established Products   2,022   1,524 33 % 27 %   540   373 45 %   1,482   1,151 29 % 22 %
      Legacy Pfizer Other Established Products   1,590   1,524 4 % -     359   373 (4 %)   1,231   1,151 7 % -  
     TOTAL DIVERSIFIED:$2,242$833169%157%$713$316126%$1,529$517196%175%
     

    ANIMAL HEALTH***

      893   648 38 % 31 %   338   261 30 %   555   387 43 % 32 %
     

    CONSUMER HEALTHCARE***

      678   - * *   327   - *   351   - * *
     

    NUTRITION***

      476   - * *   -   - *   476   - * *
     CAPSUGEL   195   185 5 % 4 %   48   55 (13 %)   147   130 13 % 10 %
     

    OTHER****

    $64$88(27%)(24%)$19$186%$45$70(36%)(33%)
                             
      * - Calculation not meaningful.
      ** - Includes direct sales under license agreement with Eisai Co., Ltd.
      *** - Legacy Wyeth products and operations. Animal Health results for the second quarter of 2010 also reflect the addition of legacy Wyeth products.
      Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends.
      Therefore, our results for the second quarter of 2009 do not include Wyeth's results of operations.
      **** - Includes revenues generated primarily from Pfizer Centersource.
      Certain amounts and percentages may reflect rounding adjustments.
       

    (1)

    Total International represents Developed Europe region + Developed Rest of World region + Emerging Markets region. Details for these regions are located on the following page.

     
    PFIZER INC.
    REVENUES
    DETAIL OF INTERNATIONAL REVENUES BY GEOGRAPHIC REGION
    SECOND QUARTER 2010
    (UNAUDITED)
    (millions of dollars)
     
     

    DEVELOPED EUROPE(1)

    DEVELOPED REST OF WORLD(2)

    EMERGING MARKETS(3)

                             
       2010  2009% Change    2010  2009% Change    2010  2009% Change  
         TotalOper.    TotalOper.    TotalOper.
    TOTAL INTERNATIONAL REVENUES$4,142$2,90942%41%$2,709$1,91042%25%$3,095$1,64189%76%
    TOTAL INTERNATIONAL BIOPHARMACEUTICAL:$3,670$2,62140%38%$2,452$1,79736%25%$2,250$1,45555%44%
    Lipitor   664   675 (2 %) (3 %)   571   475 20 % 2 %   265   221 20 % 11 %

    Enbrel (Outside the U.S. and Canada)***

      547   - * *   106   - * *   155   - * *
    Lyrica   268   221 21 % 20 %   51   34 50 % 25 %   78   50 56 % 47 %
    Effexor***   63   - * *   41   - * *   25   - * *
    Celebrex   43   49 (12 %) (9 %)   84   55 53 % 35 %   79   54 46 % 34 %
    Viagra   97   100 (3 %) (5 %)   49   38 29 % 11 %   111   78 42 % 30 %
    Xalatan / Xalacom   146   141 4 % 2 %   102   92 11 % 1 %   50   44 14 % 3 %

    Prevnar / Prevenar 13***

      69   - * *   2   - * *   15   - * *

    Prevnar / Prevenar 7***

      101   - * *   61   - * *   136   - * *
    Norvasc   55   58 (5 %) (8 %)   232   327 (29 %) (34 %)   124   117 6 % 3 %
    Zyvox   73   64 14 % 14 %   35   29 21 % 15 %   37   26 42 % 30 %
    Detrol / Detrol LA   43   47 (9 %) (12 %)   25   21 19 % 8 %   16   13 23 % 12 %

    Premarin Family***

      3   - * *   4   - * *   15   - * *
    Sutent   103   108 (5 %) (5 %)   36   21 71 % 56 %   54   38 42 % 33 %
    Geodon / Zeldox   23   23 -   (3 %)   4   3 33 % 16 %   15   13 15 % 8 %

    Zosyn / Tazocin***

      28   - * *   3   - * *   49   - * *
    Genotropin   92   86 7 % 6 %   52   45 16 % 6 %   29   26 12 % 5 %
    Vfend   72   69 4 % 3 %   34   27 26 % 15 %   38   30 27 % 21 %
    Chantix / Champix   44   38 16 % 13 %   46   31 48 % 28 %   8   7 14 % 11 %

    Benefix***

      62   - * *   22   - * *   3   - * *
    Zoloft   21   22 (5 %) (6 %)   72   52 38 % 27 %   32   29 10 % 4 %
    Caduet   5   3 67 % 108 %   24   15 60 % 17 %   13   11 18 % 12 %
    Aromasin   50   49 2 % -     18   14 29 % 15 %   13   12 8 % -  
    Revatio   32   26 23 % 19 %   9   5 80 % 51 %   6   4 50 % 42 %

    Pristiq***

      -   - * *   10   - * *   4   - * *
    Medrol   26   25 4 % 1 %   12   13 (8 %) (5 %)   45   37 22 % 18 %
    Cardura   37   42 (12 %) (11 %)   45   45 -   (8 %)   26   25 4 % (1 %)
    Zithromax / Zmax   21   26 (19 %) (20 %)   48   37 30 % 20 %   39   33 18 % 11 %
    Aricept**   58   64 (9 %) (12 %)   36   31 16 % 1 %   9   13 (31 %) (37 %)

    Refacto / Xyntha***

      73   - * *   7   - * *   -   - * *
    Alliance Revenue   133   127 5 % 2 %   160   105 52 % 40 %   18   14 29 % 44 %

    (Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge)

                           
    All Other Biopharmaceutical   618   558 11 % 10 %   451   282 60 % 45 %   743   560 33 % 24 %
    All Other Established Products   464   388 20 % 18 %   395   244 62 % 45 %   623   519 20 % 13 %
    Legacy Pfizer Other Established Products   383   388 (1 %) (3 %)   277   244 14 % 1 %   571   519 10 % 4 %
    TOTAL INTERNATIONAL DIVERSIFIED:$444$24680%79%$251$104141%98%$834$167**

    OTHER INTERNATIONAL****

    $28$42(33%)11%$6$9(33%)3%$11$19(42%)4%
                             
    * - Calculation not meaningful.
    ** - Includes direct sales under license agreement with Eisai Co., Ltd.
    *** - Legacy Wyeth products and operations. Animal Health results for the second quarter of 2010 also reflect the addition of legacy Wyeth products.
    Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends.
    Therefore, our results for the second quarter of 2009 do not do not include Wyeth's results of operations.
    **** - Includes revenues generated primarily from Pfizer Centersource.
    Certain amounts and percentages may reflect rounding adjustments.
     
     
    (1) Developed Europe region includes the following markets: Western Europe and the Scandinavian countries.
    (2) Developed Rest of World region includes the following markets: Australia, Canada, Japan, New Zealand, and South Korea.
    (3) Emerging Markets region includes, but is not limited to, the following markets: Asia (excluding Japan and South Korea), Latin America, Middle East, Africa, Central and Eastern Europe, Russia and Turkey. In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.
    PFIZER INC.
    REVENUES
    FIRST SIX MONTHS OF 2010 and 2009
    (UNAUDITED)
    (millions of dollars)
     
     WORLDWIDEUNITED STATES

    TOTAL INTERNATIONAL(1)

                           
       2010  2009% Change    2010  2009% Change  2010  2009% Change
         TotalOper.    Total    TotalOper.
    TOTAL REVENUES$34,077$21,85156%50%$14,695$9,49355%$19,382$12,35857%46%
    TOTAL BIOPHARMACEUTICAL:$29,527$20,16546%41%$13,256$8,89949%$16,271$11,26644%35%
    Lipitor   5,570   5,406 3 % (2 %)   2,623   2,766 (5 %)   2,947   2,640 12 % 2 %
    Enbrel (Outside the U.S. and Canada)***   1,610   - * *   -   - *   1,610   - * *
    Lyrica   1,485   1,312 13 % 10 %   717   742 (3 %)   768   570 35 % 26 %
    Effexor***   1,337   - * *   1,084   - *   253   - * *
    Celebrex   1,174   1,112 6 % 3 %   786   809 (3 %)   388   303 28 % 18 %
    Viagra   970   877 11 % 6 %   487   465 5 %   483   412 17 % 8 %
    Xalatan / Xalacom   871   802 9 % 4 %   296   271 9 %   575   531 8 % 1 %
    Prevnar / Prevenar 13***   855   - * *   691   - *   164   - * *
    Prevnar / Prevenar 7***   851   - * *   214   - *   637   - * *
    Norvasc   790   999 (21 %) (24 %)   24   35 (31 %)   766   964 (21 %) (24 %)
    Zyvox   591   540 9 % 7 %   315   313 1 %   276   227 22 % 16 %
    Detrol / Detrol LA   521   562 (7 %) (10 %)   352   403 (13 %)   169   159 6 % (2 %)
    Premarin Family***   516   - * *   472   - *   44   - * *
    Sutent   514   425 21 % 16 %   131   123 7 %   383   302 27 % 20 %
    Geodon / Zeldox   501   461 9 % 7 %   418   387 8 %   83   74 12 % 5 %
    Zosyn / Tazocin***   494   - * *   328   - *   166   - * *
    Genotropin   439   404 9 % 4 %   105   104 1 %   334   300 11 % 6 %
    Vfend   395   359 10 % 6 %   123   116 6 %   272   243 12 % 6 %
    Chantix / Champix   359   369 (3 %) (7 %)   178   228 (22 %)   181   141 28 % 16 %
    Benefix***   318   - * *   144   - *   174   - * *
    Zoloft   264   240 10 % 5 %   36   43 (16 %)   228   197 16 % 9 %
    Caduet   261   262 -   (5 %)   170   203 (16 %)   91   59 54 % 31 %
    Aromasin   250   224 12 % 8 %   83   81 2 %   167   143 17 % 10 %
    Revatio   236   208 13 % 11 %   144   141 2 %   92   67 37 % 29 %
    Pristiq***   223   - * *   199   - *   24   - * *
    Medrol   222   228 (3 %) (6 %)   55   76 (28 %)   167   152 10 % 6 %
    Cardura   217   221 (2 %) (6 %)   10   3 233 %   207   218 (5 %) (10 %)
    Zithromax / Zmax   213   214 -   (5 %)   6   8 (25 %)   207   206 -   (4 %)
    Aricept**   210   203 3 % (6 %)   -   - *   210   203 3 % (6 %)
    Refacto / Xyntha***   188   - * *   39   - *   149   - * *
    Alliance Revenue   2,065   1,180 75 % 72 %   1,470   711 107 %   595   469 27 % 19 %
    (Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge)                      
    All Other Biopharmaceutical   5,017   3,557 41 % 35 %   1,556   871 79 %   3,461   2,686 29 % 21 %
    All Other Established Products   3,904   2,983 31 % 27 %   1,084   778 39 %   2,820   2,205 28 % 20 %
    Legacy Pfizer Other Established Products   3,083   2,983 3 % (2 %)   743   778 (4 %)   2,340   2,205 6 % -  
    TOTAL DIVERSIFIED:$4,383$1,524188%174%$1,376$554148%$3,007$970210%188%
    ANIMAL HEALTH***   1,739   1,185 47 % 38 %   637   455 40 %   1,102   730 51 % 37 %
    CONSUMER HEALTHCARE***   1,341   - * *   642   - *   699   - * *
    NUTRITION***   934   - * *   -   - *   934   - * *
    CAPSUGEL   369   339 9 % 6 %   97   99 (2 %)   272   240 13 % 9 %
    OTHER****$167$1623%2%$63$4058%$104$122(15%)(3%)
                           
    * - Calculation not meaningful.
    ** - Includes direct sales under license agreement with Eisai Co., Ltd.
    *** - Legacy Wyeth products and operations. Animal Health results for the first six months of 2010 also reflect the addition of legacy Wyeth products.
    Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends.
    Therefore, our results for the first six months of 2009 do not include Wyeth's results of operations.
    **** - Includes revenues generated primarily from Pfizer Centersource.
    Certain amounts and percentages may reflect rounding adjustments.
     
    (1) Total International represents Developed Europe region + Developed Rest of World region + Emerging Markets region. Details for these regions are located on the following page.
    PFIZER INC.
    REVENUES
    DETAIL OF INTERNATIONAL REVENUES BY GEOGRAPHIC REGION
    FIRST SIX MONTHS OF 2010 and 2009
    (UNAUDITED)
    (millions of dollars)
     
     

    DEVELOPED EUROPE(1)

    DEVELOPED REST OF WORLD(2)

    EMERGING MARKETS(3)

                             
       2010  2009% Change    2010  2009% Change    2010  2009% Change  
         TotalOper.    TotalOper.    TotalOper.
    TOTAL INTERNATIONAL REVENUES$8,473$5,59152%45%$5,024$3,68836%21%$5,885$3,07991%79%
    TOTAL INTERNATIONAL BIOPHARMACEUTICAL:$7,508$5,04149%43%$4,541$3,48430%17%$4,222$2,74154%44%
    Lipitor   1,359   1,297 5 % -     1,108   938 18 % -     480   405 19 % 9 %
    Enbrel (Outside the U.S. and Canada)***   1,128   - * *   191   - * *   291   - * *
    Lyrica   534   410 30 % 24 %   99   65 52 % 27 %   135   95 42 % 34 %
    Effexor***   129   - * *   76   - * *   48   - * *
    Celebrex   90   89 1 % (2 %)   159   106 50 % 34 %   139   108 29 % 18 %
    Viagra   204   190 7 % 2 %   96   77 25 % 8 %   183   145 26 % 17 %
    Xalatan / Xalacom   296   269 10 % 5 %   184   180 2 % (7 %)   95   82 16 % 6 %
    Prevnar / Prevenar 13***   145   - * *   2   - * *   17   - * *
    Prevnar / Prevenar 7***   207   - * *   116   - * *   314   - * *
    Norvasc   109   113 (4 %) (8 %)   423   629 (33 %) (36 %)   234   222 5 % 2 %
    Zyvox   146   123 19 % 15 %   61   56 9 % 4 %   69   48 44 % 31 %
    Detrol / Detrol LA   90   93 (3 %) (8 %)   49   40 23 % 7 %   30   26 15 % 9 %
    Premarin Family***   5   - * *   14   - * *   25   - * *
    Sutent   218   196 11 % 7 %   64   35 83 % 63 %   101   71 42 % 33 %
    Geodon / Zeldox   47   42 12 % 8 %   8   6 33 % 25 %   28   26 8 % (6 %)
    Zosyn / Tazocin***   61   - * *   7   - * *   98   - * *
    Genotropin   187   166 13 % 7 %   91   86 6 % -     56   48 17 % 8 %
    Vfend   149   135 10 % 6 %   62   53 17 % 7 %   61   55 11 % 3 %
    Chantix / Champix   88   71 24 % 17 %   78   56 39 % 18 %   15   14 7 % 3 %
    Benefix***   125   - * *   41   - * *   8   - * *
    Zoloft   45   45 -   (3 %)   124   97 28 % 19 %   59   55 7 % 3 %
    Caduet   10   8 25 % 23 %   57   31 84 % 43 %   24   20 20 % 15 %
    Aromasin   102   93 10 % 5 %   30   26 15 % 5 %   35   24 46 % 36 %
    Revatio   64   50 28 % 22 %   16   10 60 % 53 %   12   7 71 % 50 %
    Pristiq***   -   - * *   17   - * *   7   - * *
    Medrol   52   49 6 % 1 %   22   25 (12 %) (12 %)   93   78 19 % 14 %
    Cardura   78   81 (4 %) (8 %)   80   89 (10 %) (14 %)   49   48 2 % (4 %)
    Zithromax / Zmax   46   64 (28 %) (32 %)   81   76 7 % 2 %   80   66 21 % 16 %
    Aricept**   119   125 (5 %) (9 %)   72   56 29 % 6 %   19   22 (14 %) (20 %)
    Refacto / Xyntha***   136   - * *   13   - * *   -   - * *
    Alliance Revenue   269   240 12 % 7 %   289   201 44 % 34 %   37   28 32 % 29 %
    (Enbrel (in the U.S. and Canada)***, Aricept, Rebif, and Exforge)                        
    All Other Biopharmaceutical   1,270   1,092 16 % 12 %   811   546 49 % 36 %   1,380   1,048 32 % 23 %
    All Other Established Products   960   766 25 % 20 %   711   472 51 % 37 %   1,149   967 19 % 12 %
    Legacy Pfizer Other Established Products   793   766 4 % (1 %)   499   472 6 % (5 %)   1,048   967 8 % 2 %
    TOTAL INTERNATIONAL DIVERSIFIED:$902$48088%80%$468$184154%112%$1,637$306**
    OTHER INTERNATIONAL****$63$70(10%)15%$15$20(25%)3%$26$32(19%)12%
                             
    * - Calculation not meaningful.
    ** - Includes direct sales under license agreement with Eisai Co., Ltd.
    *** - Legacy Wyeth products and operations. Animal Health results for the first six months of 2010 also reflect the addition of legacy Wyeth products.
    Wyeth's results are included in our financial statements commencing from the acquisition date of October 15, 2009, in accordance with Pfizer's domestic and international year-ends.
    Therefore, our results for the first six months of 2009 do not include Wyeth's results of operations.
    **** - Includes revenues generated primarily from Pfizer Centersource.
    Certain amounts and percentages may reflect rounding adjustments.
     
     
    (1) Developed Europe region includes the following markets: Western Europe and the Scandinavian countries.
    (2) Developed Rest of World region includes the following markets: Australia, Canada, Japan, New Zealand, and South Korea.
    (3) Emerging Markets region includes, but is not limited to, the following markets: Asia (excluding Japan and South Korea), Latin America, Middle East, Africa, Central and Eastern Europe, Russia and Turkey. In Biopharmaceutical, revenues from South Korea in 2009 have been reclassified from the Emerging Markets unit to the appropriate developed market units to conform to the current-year presentation, which reflects the fact that the commercial operations of South Korea, effective January 1, 2010, are managed within the appropriate developed market units.

    PFIZER INC.

    SUPPLEMENTAL INFORMATION

    1. Change in Reported Cost of Sales

    Reported cost of sales increased 116% in the second quarter of 2010, compared to the same period in 2009, and increased 156% in the first six months of 2010, compared to the same period in 2009. The increases primarily reflect purchase accounting adjustments associated with the Wyeth acquisition, the addition of Wyeth manufacturing costs, as well as the change in the mix of products and businesses as a result of the Wyeth acquisition. In addition, the impact of foreign exchange had a favorable impact on reported cost of sales in the second quarter of 2010 and an unfavorable impact for the first six months of 2010.

    Reported cost of sales as a percentage of revenues increased 5.9 percentage points to 21.9% in second-quarter 2010, compared to the same period in 2009, reflecting the aforementioned factors.

    2. Change in Reported Selling, Informational & Administrative (SI&A) Expenses and Reported Research & Development (R&D) Expenses and Reported In-Process R&D (IPR&D) Charges

    Reported SI&A expenses increased 43% in the second quarter of 2010, compared to the same period in 2009, and increased 48% in the first six months of 2010, compared to the same period in 2009. The increases primarily reflect the addition of Wyeth operating costs and the unfavorable impact of foreign exchange.

    Reported R&D expenses increased 29% in the second quarter of 2010, compared to the same period in 2009, and increased 30% in the first six months of 2010, compared to the same period in 2009. The increases are primarily due to the addition of legacy Wyeth operations, continued investment in the late-stage development portfolio and the unfavorable impact of foreign exchange.

    Reported IPR&D charges of $74 million recorded in the first six months of 2010 relate to the resolution of contingencies associated with our 2008 acquisition of CovX.

    3. Other (Income)/Deductions - Net

       
      ($ in millions)   Second Quarter   Six Months
          2010     2009     2010     2009  
      Interest income(a)

    Interest income

    $ (85 ) $ (204 ) $ (197 ) $ (449 )
      Interest expense(a)   389     270     911     400  
      Net interest (income)/expense   304     66     714     (49 )
      Royalty-related income   (95 )   (50 )   (237 )   (107 )
      Net gain on asset disposals   (185 )   (29 )   (230 )   (41 )
      Legal matters, net   37     (19 )   174     77  
      Asset impairment charges   196     71     232     89  
      Other, net   14     33     32     46  
      Other (income)/deductions-net $ 271   $ 72   $ 685   $ 15  

    (a)

    Interest expense increased in 2010 due to our issuance of $13.5 billion of senior unsecured notes on March 24, 2009 and $10.5 billion of senior unsecured notes on June 3, 2009, primarily related to the acquisition of Wyeth. Interest income decreased in 2010 due to lower interest rates coupled with lower average cash balances.

    4. Effective Tax Rate

    The effective tax rate on reported Income from continuing operations before provision for taxes on income for second-quarter 2010 was 37.4% compared to 25.8% in the second quarter of 2009, and in the first six months of 2010 was 36.8% compared to 27.1% in the first six months of 2009. The increases in the effective tax rate primarily are the result of higher charges, incurred as a result of our acquisition of Wyeth, and the mix of jurisdictions in which those charges were incurred. In addition, the increases in the effective tax rate were impacted by the expiration of the U.S. research tax credit and, in the first six months of 2010 compared to the first six months of 2009, the write-off of the deferred tax asset of approximately $270 million related the Medicare Part D subsidy for retiree prescription drug coverage resulting from changes in the recently enacted U.S. healthcare legislation concerning the tax treatment of that subsidy effective for tax years beginning after December 31, 2012, partially offset by $410 million in tax benefits for the resolution of certain tax positions pertaining to prior years with various foreign tax authorities.

    The effective tax rate on adjusted income(1) was 31.7% in second-quarter 2010 compared to 28.1% in second-quarter 2009, and in the first six months of 2010 was 30.9% compared to 29.0% in the first six months of 2009. The increases in the tax rate on adjusted income(1) primarily are the result of certain business decisions made in connection with the acquisition of Wyeth and the change in jurisdictional mix of earnings. In addition, the increases in the effective tax rate were impacted by the expiration of the U.S. research tax credit and, in the first six months of 2010 compared to the first six months of 2009, the write-off of the deferred tax asset of approximately $270 million related the Medicare Part D subsidy for retiree prescription drug coverage resulting from changes in the recently enacted U.S. healthcare legislation concerning the tax treatment of that subsidy effective for tax years beginning after December 31, 2012, largely offset by $410 million in tax benefits for the resolution of certain tax positions pertaining to prior years with various foreign tax authorities.

    5. Reconciliation of 2010 Adjusted Income(1) and Adjusted Diluted EPS(1) Guidance to 2010 Reported Net Income Attributable to Pfizer Inc. and Reported Diluted EPS Attributable to Pfizer Inc. Common Shareholders Guidance (a)

     
       Full-Year 2010 Guidance
      ($ billions, except per-share amounts)

    Net Income(b)

    Diluted EPS(b)

     Income/(Expense)    
      Adjusted Income/Diluted EPS(1) Guidance ~$17.0 - $17.8 ~$2.10 - $2.20
      Purchase Accounting Impacts of Transactions Completed as of 7/4/10 (6.3) (0.78)
      Acquisition-Related Costs (2.4 – 2.8) (0.29-0.34)
      Certain Significant Items(0.2)(0.03)
      Reported Net Income Attributable to Pfizer Inc./Diluted EPS Guidance ~$7.7 - $8.9 ~$0.95 - $1.10
     
    (a) The current exchange rates assumed in connection with the 2010 financial guidance are a blend of the average of the actual
    exchange rates in effect during first-half 2010 and the mid-July 2010 exchange rates for the remainder of the year.
     
    (b) Does not assume the completion of any business-development transactions not completed as of July 4, 2010. Amounts exclude
    the potential effects of the resolution of litigation-related matters not substantially resolved as of July 4, 2010.

    6. Reconciliation of 2012 Adjusted Income(1) and Adjusted Diluted EPS(1) Targets to 2012 Reported Net Income Attributable to Pfizer Inc. and Reported Diluted EPS Attributable to Pfizer Inc. Common Shareholders Targets (a)

       
       Full-Year 2012 Targets
      ($ billions, except per-share amounts)

    Net Income(b)

    Diluted EPS(b)

     Income/(Expense)    
      Adjusted Income/Diluted EPS(1) Targets ~$18.3 - $19.1 ~$2.25 - $2.35
      Purchase Accounting Impacts of Transactions Completed as of 7/4/10 (3.8) (0.47)
      Acquisition-Related Costs(1.2 – 1.6)(0.15 – 0.20)
      Reported Net Income Attributable to Pfizer Inc./Diluted EPS Targets ~$12.9 - $14.1 ~$1.58 - $1.73
           

    (a)

    The current exchange rates assumed in connection with the 2012 financial targets are the mid-July 2010 exchange rates.

    (b)

    Given the longer-term nature of these targets, they are subject to greater variability and less certainty as a result of potential material impacts related to foreign exchange fluctuations, macroeconomic activity including inflation, and industry-specific challenges including changes to government healthcare policy, among others.

     

     

     
     

    (1) "Adjusted income" and "adjusted diluted earnings per share (EPS)" are defined as reported net income attributable to Pfizer Inc. and reported diluted EPS attributable to Pfizer Inc. common shareholders excluding purchase accounting adjustments, acquisition-related costs, discontinued operations and certain significant items. As described under Adjusted Income in the Management's Discussion and Analysis of Financial Condition and Results of Operations section of Pfizer's Form 10-Q for the fiscal quarter ended April 4, 2010, management uses adjusted income, among other factors, to set performance goals and to measure the performance of the overall company. We believe that investors' understanding of our performance is enhanced by disclosing this measure. The adjusted income and adjusted diluted EPS measures are not, and should not be viewed as, substitutes for U.S. GAAP net income and diluted EPS.

    DISCLOSURE NOTICE: The information contained in this earnings release and the attachments is as of August 3, 2010. The Company assumes no obligation to update forward-looking statements contained in this earnings release or the attachments as a result of new information or future events or developments.

    This earnings release and the attachments contain forward-looking information about the Company's financial results and estimates, business plans and prospects, in-line products and product candidates that involves substantial risks and uncertainties. You can identify these statements by the fact that they use words such as "will," "anticipate," "estimate," "expect," "project," "intend," "plan," "believe," "target," "forecast" and other words and terms of similar meaning in connection with any discussion of future operating or financial performance or business plans and prospects. Among the factors that could cause actual results to differ materially are the following: the success of research and development activities; decisions by regulatory authorities regarding whether and when to approve our drug applications as well as their decisions regarding labeling, ingredients and other matters that could affect the availability or commercial potential of our products; the speed with which regulatory authorizations, pricing approvals and product launches may be achieved; the success of external business-development activities; competitive developments, including the impact on our competitive position of new product entrants, in-line branded products, generic products, private label products and product candidates that treat diseases and conditions similar to those treated by our in-line drugs and drug candidates; the ability to meet generic and branded competition after the loss of patent protection for our products or competitor products; the ability to successfully market both new and existing products domestically and internationally; difficulties or delays in manufacturing; trade buying patterns; the impact of existing and future legislation and regulatory provisions on product exclusivity; trends toward managed care and healthcare cost containment; the impact of U.S. healthcare legislation enacted in 2010 – the Patient Protection and Affordable Care Act, as amended by the Health Care and Education Reconciliation Act; U.S. legislation or regulatory action affecting, among other things, pharmaceutical product pricing, reimbursement or access, including under Medicaid, Medicare and other publicly funded or subsidized health programs, the importation of prescription drugs from outside the U.S. at prices that are regulated by governments of various foreign countries, direct-to-consumer advertising and interactions with healthcare professionals, and the use of comparative effectiveness methodologies that could be implemented in a manner that focuses primarily on the cost differences and minimizes the therapeutic differences among pharmaceutical products and restricts access to innovative medicines; legislation or regulatory action in markets outside the U.S. affecting pharmaceutical product pricing, reimbursement or access; contingencies related to actual or alleged environmental contamination; claims and concerns that may arise regarding the safety or efficacy of in-line products and product candidates; significant breakdown, infiltration, or interruption of our information technology systems and infrastructure; legal defense costs, insurance expenses, settlement costs and the risk of an adverse decision or settlement related to product liability, patent protection, governmental investigations, ongoing efforts to explore various means for resolving asbestos litigation, and other legal proceedings; the Company's ability to protect its patents and other intellectual property both domestically and internationally; interest rate and foreign currency exchange rate fluctuations; governmental laws and regulations affecting domestic and foreign operations, including tax obligations and changes affecting the taxation by the U.S. of income earned outside of the U.S. that may result from pending and possible future proposals; changes in U.S. generally accepted accounting principles; uncertainties related to general economic, political, business, industry, regulatory and market conditions including, without limitation, uncertainties related to the impact on us, our lenders, our customers, our suppliers and counterparties to our foreign-exchange and interest-rate agreements of weak global economic conditions and recent and possible future changes in global financial markets; any changes in business, political and economic conditions due to actual or threatened terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas; growth in costs and expenses; changes in our product, segment and geographic mix; and the impact of acquisitions, divestitures, restructurings, product withdrawals and other unusual items, including our ability to realize the projected benefits of our acquisition of Wyeth and of our cost-reduction initiatives. A further list and description of risks, uncertainties and other matters can be found in the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2009 and in its reports on Forms 10-Q and 8-K.

    This earnings release may include discussion of certain clinical studies relating to various in-line products and/or product candidates. These studies typically are part of a larger body of clinical data relating to such products or product candidates, and the discussion herein should be considered in the context of the larger body of data.

     

    Pfizer Inc.
    Media:
    Joan Campion, +1-212-733-2798
    or
    Investors:
    Suzanne Harnett, +1-212-733-8009

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