St. Louis, MO Site Statistics:

• Two locations with 250,000-square-feet laboratory & manufacturing space and 70,000-square-feet office space

Functions: WRD – BioTherapeutics Pharmaceutical Sciences

Key Technologies: Bioprocess Sciences, Analytical Technologies, Pharmaceutic Protein Formulation Development, BioTherapeutics scale-up and GMP Pilot Plants

Worldwide Research and Development's St. Louis laboratories are focused in the area of Biotherapeutics and Vaccines development. The BioTherapeutics Pharmaceutical Sciences laboratories help prepare biologic (protein molecules) therapies and vaccines for clinical trials. The group is responsible for developing novel manufacturing processes, analytical controls, formulations, as well as, providing data required for regulatory submissions. Biologics and vaccines for Phase 1 and Phase 2 clinical trials are manufactured at the St. Louis Pilot Plant under cGMP. Additionally, the St. Louis laboratories develop Phase 3 commercial processes and transfer this technology to Pfizer Global Supply.

In recent years St. Louis labs and colleagues are proud to have played a significant role in bringing Celebrex^®, Inspra^®, Genotropin^® and Somavert^® to patients.

Currently the St. Louis groups are based at two locations, Chesterfield and Weldon Spring.