A Study Comparing Combination of Encorafenib + Binimetinib as a Standard-dose and a High dose Regimen in Patients with BRAFV600-Mutant Melanoma Brain Metastasis. A Phase 2, Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-Mutant Melanoma Brain Metastasis.