Clinical Study Report Synopses
Clinical Study Reports (CSRs) are often created as part of the process of submitting applications for new medical treatments to regulators. CSRs answer questions such as: Why was the trial done? What were the important questions asked in the trial? What were the results? CSRs also include extensive details on the course of treatment for patients, the medical information collected from the patients as part of the research, and demographic data, as well as other kinds of information to explain how the trial was conducted and results were analyzed.
Because CSRs contain information that could be valuable to researchers, Pfizer is making electronic synopses of CSRs publicly available on this website. They include the synopsis of the CSR submitted to the regulatory agency.
Any data that could be used to identify individual patients has been removed. Synopses will be posted for trials either initiated after Sept. 27, 2007, or trials initiated on or before that date that were still ongoing as of Dec. 26, 2007. To access the synopses that have been posted to date, press the "Show Results" button to see the full list, or filter the results using the fields below.
* The NCT Number is the ClinicalTrials.gov unique identifier for a specific study.
Science & Innovation
The Next Era of Decentralized Clinical Trials: The Clinical Trial Anywhere Model
During the early months of 2020, decentralized modalities to conduct clinical trials went mainstream as a solution to a short-term problem: how to continue clinical trials amid pandemic closures.
Purpose & Ideals
Clinical Trial Innovation: Putting the Patient First in Clinical Trial Design
Every day, across the United States and around the world, scientists are developing potential new medicines and vaccines that could change lives.
Programs & Initiatives
The Importance of Returning Clinical Trial Data to Participants
Clinical trial participants are at the heart of medical research, and it’s with their help that Pfizer is able to bring life-changing treatments to patients.But, until recently, clinical trial sponsors like Pfizer have not been equipped to provide participants with their own personal clinical trial
Anatomy of a Clinical Trial: The Purpose, People, and Phases of Clinical Research
From 2010 to July 2021, ClinicalTrials.gov reports that the number of registered clinical trials more than tripled, growing from 100,208 to 384,288 and counting.1 The race for a COVID-19 vaccine made clinical trials headline news in 2020 and 2021, with thousands of people worldwide volunteering to
Translating Technical Language into Plain Language for Clinical Trials
"Adjuvant therapy." "Pharmacologic effect." "Standard-of-care." These aren't terms used by most people in everyday conversation. But this kind of medical terminology has long been a part of clinical trial summaries, making it daunting for many people to understand what they're reading.
Living & Wellbeing
Do You Have What It Takes to Join a Phase 1 Clinical Trial?
“Life's most persistent and urgent question is: What are you doing for others?” ~ Martin Luther King, Jr. For some, volunteering at their local food bank is a preferred way to give back. Some donate money to organizations or non-profits they believe in. Others donate blood.
Purpose & Ideals
Doing Better: Increasing Diversity in Clinical Trials
Diversity in clinical trials is key to equitable health outcomes. Increasingly, clinicians, researchers and patients are realizing that a lack of diversity in clinical trial participants may contribute to the stubborn persistence of health disparities, such as the fact that Black Americans are 30%
The Phases of a Clinical Trial
Understanding the Phases of Clinical Trials Prescription drugs don’t just show up on pharmacy shelves one day.
Differences Can Make a Big Difference
People from different racial and ethnic groups have different biological responses to both diseases and their treatment.
Exploring the Manufacturing and Testing Processes of Pharmaceuticals
When a doctor prescribes you a medicine, how does she know it could be helpful?
Clinical Trial Practices—Safeguards in Research
If you or a loved one is considering joining a clinical trial, you may be happy to know that research studies today have strict safeguards, standards of ethics, and are highly regulated.
Joining a Clinical Trial: What to Know Before You Enroll
As a scientist who has been involved in running clinical trials for the past 30 years, I have seen first-hand how patients have contributed to and benefited from participating in a clinical trial.
Clinical Trials for Children – Why Are They So Important?
When doctors prescribe a medication, they may rely on the drug label (or US prescribing information) to help them understand how to use it safely and successfully.
What If You Could Donate Your Data For Research?
There are many ways you can help researchers learn more about certain conditions or diseases by sharing your data. Being an active participant in a study that involves medical testing is not the only way scientific data is gathered in research studies and clinical trials.
Caregiver’s Guide for Parkinson’s Disease
Parkinson’s disease (PD) is a complex neurodegenerative motor disorder, meaning there are many features of the disease that will change over time—slowly in most people.
The Importance of Women and Diversity in Clinical Trials
Clinical trials are key to finding and learning if medical treatments are safe and effective. These treatments include medicines, medical devices, procedures, and lifestyle changes, such as diet. All new medical treatments must go through clinical trials before they can be approved by the FDA.
Does Being a Person of Color Increase Your Health Risks?
The US has become more ethnically diverse in the last century, and in general our health and the quality of care we receive has improved. Unfortunately, this isn’t always the case for some people of color.
Real People
Latino Colleagues at Pfizer Are Developing Potential Solutions for People Affected by COVID-19
Traditionally, National Hispanic Heritage Month is marked from September 15th to October 15th and honors the cultures and contributions of Hispanic and Latino Americans.
Science & Innovation
Other Diseases Deserve the Same Acceleration as COVID-19
Please see the attached PDF file to be uploaded to Our Science section.
Science & Innovation
Vaccine Production: Find Out How Vaccines Are Created
Vaccines have revolutionized our ability to improve health and save lives, resulting in the control, elimination, or near-elimination of many life-threatening diseases.