Scientist, Display Technologies

United States - Washington – Bothell

Full time

Posted 2 Days Ago

4916791

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Scientist, you will be at the center of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be part of Pfizer's Worldwide Research and Development team that employs a multidisciplinary approach to identify and target cancer cell cycle for developing the next generation Oncology therapeutics and therapeutic combinations. You will contribute to early discovery and protein engineering for the development of novel biotherapeutics. You will be responsible for supporting therapeutic projects by discovering antibodies via phage display and characterizing resulting molecules. The successful candidate will possess expertise in both antibody-discovery methods, molecular biology, and in vitro assays, such as SPR. With your deep knowledge in the discipline, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You will undertake mentoring activities to guide your team members.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

Perform phage panning against a variety of antigen sources and formats under the supervision of more senior team members
Serve as a subject-matter expert on project teams and represent the Display Technologies group
Generate recombinant antibodies and antibody fragments from bacteria and mammalian cells
Assay binding of recombinant antibodies using a variety of techniques (e.g., ELISA, SPR, BLI, etc.)
Perform epitope-binning experiments with panels of antibodies
Keep an up-to-date and accurate electronic laboratory notebook
Participate in group meetings and other relevant team meetings
Present protocols and data related to phage-display campaigns within individual and project team meetings
Interact directly with cross-functional teams to coordinate and plan inter-group tasks
Assist with innovation projects related to display technologies, antibody discovery, and antibody characterization
Evaluate data and provide clear reports that can be shared and transferred to and from cross-functional teams.
Pay attention to detail, strictly adhere to safety protocols, and use knowledge of basic laboratory procedures to advance projects under rapidly shifting priorities and timelines.

Qualifications

Must-Have

Bachelor's Degree
6+ years of experience
Experience in protein-based assays (e.g., ELISA, SPR, or BLI)
Experience culturing mammalian cell lines, including practicing good aseptic technique
Familiarity with at least one antibody discovery or display technology (e.g., phage display, yeast display, mammalian display, hybridoma, or single B-cell cloning) is a plus
Ability to collaborate across teams
Demonstrated ability to work independently
Ability to plan, manage, and organize their work with minimal oversight
Strong written and verbal communication skills, including ability to maintain a good working laboratory notebook

Nice-to-Have

Knowledge of antibody drug conjugates (ADCs), antibody-based therapeutics, and antibody discovery
Knowledge of protein expression and purification (bacterial or mammalian)

Additional Information:

Work Location: On Premist
Last Day to Apply: July 31, 2024

The annual base salary for this position ranges from $74,900.00 to $124,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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